Feb. 26, 2026
When it comes to pet deworming, topical drops and oral tablets are the two most common forms, each with unique advantages and drawbacks. Many pet owners struggle to decide which one suits their furry friends best. Veterinarians break down their key differences, helping you make an informed choice based on your pet’s lifestyle, personality, and health condition.
Topical drops, applied directly to the pet’s skin (usually between the shoulder blades), are popular for their ease of use. They require no forcing pets to swallow pills, making them ideal for picky eaters or aggressive pets. Most topical products offer broad-spectrum protection against external parasites like fleas and ticks, with some also targeting internal worms. They are absorbed through the skin and provide long-lasting protection (usually 30 days). However, they have downsides: they may leave a greasy residue on fur, can be washed off by frequent bathing, and some pets may experience skin irritation at the application site.
Oral tablets are ingested by pets and work quickly to eliminate internal parasites such as roundworms, tapeworms, and hookworms. They are not affected by bathing and leave no residue on fur, making them suitable for pets that love water. Many oral dewormers are formulated as chewable treats, which are more acceptable to most pets. On the downside, administering pills can be challenging for uncooperative pets. Some oral products may cause temporary gastrointestinal discomfort, such as vomiting or diarrhea, especially if given on an empty stomach. They also typically require more frequent administration for external parasite protection.
Choose topical drops if you have a picky or aggressive pet, or if your pet needs long-lasting external parasite protection. Opt for oral tablets if your pet is easy to medicate, loves water, or needs targeted internal deworming. For comprehensive protection, some owners combine both forms under veterinary guidance. Always follow weight-based dosing and select pet-specific products to ensure safety and efficacy.